Structure of PDB 5jq1 Chain B

Receptor sequence
>5jq1B (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
CCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQ
HHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGG
EDCAHFTDDGRWNDDVCQRPYRWVCETEL
3D structure
PDB5jq1 Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor.
ChainB
Resolution1.83 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA B D215 D242 E252 D253 D64 D91 E101 D102
BS02 CA B Q239 D241 E252 N264 D265 Q88 D90 E101 N113 D114
BS03 ZPF B Q239 D241 E252 N264 Q88 D90 E101 N113 BindingDB: Kd=7180nM
BS04 CA B V190 E196 E277 V39 E45 E126
External links
PDB RCSB:5jq1, PDBe:5jq1, PDBj:5jq1
PDBsum5jq1
PubMed28230359
UniProtP07306|ASGR1_HUMAN Asialoglycoprotein receptor 1 (Gene Name=ASGR1)

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