Structure of PDB 5jpv Chain B

Receptor sequence
>5jpvB (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
CPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQH
HIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGE
DCAHFTDDGRWNDDVCQRPYRWVCETEL
3D structure
PDB5jpv Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GAL B Q239 D241 W243 E252 N264 Q87 D89 W91 E100 N112
BS02 CA B D215 D242 E252 D253 D63 D90 E100 D101
BS03 CA B Q239 D241 E252 N264 D265 Q87 D89 E100 N112 D113
BS04 CA B V190 E196 E277 V38 E44 E125
External links
PDB RCSB:5jpv, PDBe:5jpv, PDBj:5jpv
PDBsum5jpv
PubMed28230359
UniProtP07306|ASGR1_HUMAN Asialoglycoprotein receptor 1 (Gene Name=ASGR1)

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