Structure of PDB 5jjv Chain B

Receptor sequence

>5jjvB (length=356) Species: 85962 (Helicobacter pylori 26695)

SMKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELN
QACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKARLITERLAFN
SLKNIDEVMLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEK
SYIYNITLKNISGNKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIK
IIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIES
LLKEWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREK
NGAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEA
ASIWEE

3D structure

• PDB: 5jjv Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.
• Chain: B
• Resolution: 2.4 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	B	K62 R65 N66 L77 L120 S121 A123 T124 N127 S193 R199 R213 K239 N277 Q278 T284 A286 Y287 K290 K305 H309 R312 H313 H335 Y344	K63 R66 N67 L78 L121 S122 A124 T125 N128 S188 R194 R208 K234 N272 Q273 T279 A281 Y282 K285 K300 H304 R307 H308 H330 Y339
BS02	dna	B	K26 L30 S31 L70 G71 T74 Y75 R129 I130 N159 S214 N215 K239 G240 Q285 Y289 G307 H309	K27 L31 S32 L71 G72 T75 Y76 R130 I131 N160 S209 N210 K234 G235 Q280 Y284 G302 H304

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0009037 tyrosine-based site-specific recombinase activity

Biological Process

• GO:0006310 DNA recombination
• GO:0007059 chromosome segregation
• GO:0015074 DNA integration
• GO:0051301 cell division

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:5jjv, PDBe:5jjv, PDBj:5jjv
• PDBsum: 5jjv
• PubMed: 28009253
• UniProt: O25386|XERH_HELPY Tyrosine recombinase XerH (Gene Name=xerH)