Structure of PDB 5jjm Chain B

Receptor sequence
>5jjmB (length=251) Species: 9606 (Homo sapiens) [Search protein sequence]
CQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW
AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDL
VFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPV
DGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQP
IARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
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3D structure
PDB5jjm Structure of the homodimeric androgen receptor ligand-binding domain.
ChainB
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B C669 D839 P849 C852 C1 D171 P181 C184
BS02 peptide B V713 K720 M734 M894 V45 K52 M66 M226
BS03 DHT B L701 L704 N705 Q711 F764 T877 L33 L36 N37 Q43 F96 T209 BindingDB: IC50=>10000nM,EC50=6nM,Ki=0.2nM
External links
PDB RCSB:5jjm, PDBe:5jjm, PDBj:5jjm
PDBsum5jjm
PubMed28165461
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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