Structure of PDB 5jgq Chain B

Receptor sequence
>5jgqB (length=154) Species: 9606 (Homo sapiens) [Search protein sequence]
KCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYR
EWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIK
EGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYG
CKIT
3D structure
PDB5jgq Architecture and hydration of the arginine-binding site of neuropilin-1.
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6JY B Y297 T316 D320 S346 T349 Y353 G414 I415 Y24 T43 D47 S73 T76 Y80 G141 I142 PDBbind-CN: -logKd/Ki=4.62,Kd=24uM
External links
PDB RCSB:5jgq, PDBe:5jgq, PDBj:5jgq
PDBsum5jgq
PubMed29430837
UniProtO14786|NRP1_HUMAN Neuropilin-1 (Gene Name=NRP1)

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