Structure of PDB 5jft Chain B

Receptor sequence
>5jftB (length=235) Species: 7955 (Danio rerio) [Search protein sequence]
AFRYSLNYPNIGHCIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGY
IVKVYNDQTVAQIMQVLTTVAHDDHSRCASLVCVLLSHGDEGVFFGTDTS
VDLKSLTSLFRGDRCPSLVGKPKLFFIQACRGTELDPGVETRERIPVEAD
FLYAYSTVPGYYSWRNTMTGSWFIQSLCEMMTKYGSELELLQIMTRVNHK
VALDFESTSNMPGFDAKKQIPCIVSMLTKEMYFTP
3D structure
PDB5jft Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish.
ChainB
Resolution2.28 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N65 P66 H124 G125 C166 R167
Catalytic site (residue number reindexed from 1) N29 P30 H88 G89 C130 R131
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R67 Q164 C166 Y209 S210 W211 R212 N213 T214 S254 R31 Q128 C130 Y162 S163 W164 R165 N166 T167 S207
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5jft, PDBe:5jft, PDBj:5jft
PDBsum5jft
PubMed27577093
UniProtA0A2R8QUC0

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