Structure of PDB 5jcj Chain B

Receptor sequence
>5jcjB (length=248) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNK
ERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPT
PLVKTVETQVAELIGTNAIAPFLLTMSFAQRQNLSIVNLCDAMVDQPCMA
FSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDK
WRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA
3D structure
PDB5jcj Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
ChainB
Resolution1.76 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R14 D161 Y174 K178
Catalytic site (residue number reindexed from 1) R14 D141 Y154 K158
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B R14 I15 H33 Y34 H35 N36 S37 L63 N93 A94 S95 T126 L159 D161 K178 S207 R14 I15 H33 Y34 H35 N36 S37 L63 N93 A94 S95 T116 L139 D141 K158 S187
BS02 6JM B S95 F97 Y174 V206 L208 W221 S95 F97 Y154 V186 L188 W201
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0047040 pteridine reductase activity

View graph for
Molecular Function
External links
PDB RCSB:5jcj, PDBe:5jcj, PDBj:5jcj
PDBsum5jcj
PubMed27411733
UniProtO76290

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