Structure of PDB 5j8o Chain B

Receptor sequence
>5j8oB (length=124) Species: 9606 (Homo sapiens) [Search protein sequence]
AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQF
VHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMIS
YGGADYKRITVKVNAPYAAALEHH
3D structure
PDB5j8o Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 6GZ B Y56 M115 A121 D122 Y39 M98 A104 D105 BindingDB: IC50=146nM
External links
PDB RCSB:5j8o, PDBe:5j8o, PDBj:5j8o
PDBsum5j8o
PubMed27083005
UniProtQ9NZQ7|PD1L1_HUMAN Programmed cell death 1 ligand 1 (Gene Name=CD274)

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