Structure of PDB 5j75 Chain B

Receptor sequence

>5j75B (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]

VQLVESEAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGT
IPIFGTADYAQEFQGRVTITTDESTSTAYMELSGLRSEDTAVYYCVLLGT
TMVTGHYFDYWGQGTLVTVSSNFMLTQPPSASGTPGQSVTISCSGSGSNI
GNNKVNWYQQLPGTAPKLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGL
QSEDEADYYCAAWDDGLSGYVFGTGTKLTVLAA

3D structure

PDB

5j75 Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair.

Chain

Resolution

2.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	6GQ	B	F55 T57 W234	F54 T56 W213	MOAD: Ki=0.63nM
BS02	6GQ	B	S35 W47 G50 T57 A58 D59 L99 Y179 Y241	S34 W46 G49 T56 A57 D58 L98 Y158 Y220	MOAD: Ki=0.63nM

External links

PDB	RCSB:5j75, PDBe:5j75, PDBj:5j75
PDBsum	5j75
PubMed	26442911

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