Structure of PDB 5j19 Chain B

Receptor sequence
>5j19B (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
EFGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKW
VDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLT
VSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTW
FRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRL
SLLEEYGCCKELASRLRYARTMVDKLLSSR
3D structure
PDB5j19 Phospho-Pon Binding-Mediated Fine-Tuning of Plk1 Activity
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B W414 V415 D416 Y417 Y485 H489 L490 L491 R516 F535 H538 K540 W50 V51 D52 Y53 Y121 H125 L126 L127 R152 F171 H174 K176
External links
PDB RCSB:5j19, PDBe:5j19, PDBj:5j19
PDBsum5j19
PubMed27238966
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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