Structure of PDB 5ium Chain B

Receptor sequence
>5iumB (length=195) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
EDANERIAELVKLEERQRIARDLHDTLGQKLSLIGLKSDLARKLIYKDPE
QAARELKSVQQTARTSLNEVRKIVSSMKGIRLKDELINIKQILEAAIMFI
YEEEENISLLNENILSMCLKEAVTNVVKHSQAKRVDIQQLWKEVVITVSD
DGTFKGEENSFSKGHGLLGMRERLEFANGSLHITENLTMAIPNNS
3D structure
PDB5ium Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
ChainB
Resolution3.162 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP B E289 N293 K296 H297 S298 F324 K325 G326 G334 H335 G336 E121 N125 K128 H129 S130 F154 K155 G156 G164 H165 G166
BS02 MG B E289 N293 E121 N125
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0046983 protein dimerization activity
Biological Process
GO:0000160 phosphorelay signal transduction system
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ium, PDBe:5ium, PDBj:5ium
PDBsum5ium
PubMed27938660
UniProtO34757|DESK_BACSU Sensor histidine kinase DesK (Gene Name=desK)

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