Structure of PDB 5iqk Chain B

Receptor sequence
>5iqkB (length=270) Species: 77133 (uncultured bacterium) [Search protein sequence]
TPGCEVCATWNADQAPFRLFGNTYYVGMKGLSSVLVTSPQGHVLIDGGLP
ESAPKIIANIGALGFRIEDVKLILNSHGHIDHAGGLAELQRRSNALVAAS
PSAALDLASGEVGPDDPQYHALPKYPPVKDMRLARDGGQFNVGPVYLTAH
ATPGHTPGGLSWTWQSCDGPRCLNMVYADSINAVSRPGFKFSASSEYPNA
LADLRHSFETLEKLPCDVLISAHPEASQLWQRLEASATGGSDAFVDPQAC
RAYVAAARTLLDSRLDQEKQ
3D structure
PDB5iqk Structural and Biochemical Characterization of Rm3, a Subclass B3 Metallo-beta-Lactamase Identified from a Functional Metagenomic Study.
ChainB
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H108 H110 D112 H113 H186 F220 H254
Catalytic site (residue number reindexed from 1) H77 H79 D81 H82 H155 F189 H223
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C35 C38 C4 C7
BS02 ZN B C198 C203 C167 C172
BS03 ZN B H108 H110 H186 H77 H79 H155
BS04 ZN B D112 H113 H254 D81 H82 H223
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
GO:0046872 metal ion binding
Biological Process
GO:0030655 beta-lactam antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5iqk, PDBe:5iqk, PDBj:5iqk
PDBsum5iqk
PubMed27431213
UniProtA0A059Q5E8

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