Structure of PDB 5iqf Chain B

Receptor sequence
>5iqfB (length=296) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
YDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTK
FSTGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFL
TPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEY
ILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLL
DGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNI
DIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYK
3D structure
PDB5iqf Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2)-Ia.
ChainB
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.7.1.190: aminoglycoside 2''-phosphotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B I208 G211 D213 S214 I224 K226 Y274 I277 F281 H379 I392 D393 I30 G33 D35 S36 I46 K48 Y92 I95 F99 H197 I210 D211
BS02 MG B H379 D393 H197 D211
External links
PDB RCSB:5iqf, PDBe:5iqf, PDBj:5iqf
PDBsum5iqf
PubMed27161980
UniProtP0A0C1|AACA_STAAU Bifunctional AAC/APH (Gene Name=aacA-aphD)

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