Structure of PDB 5i7m Chain B

Receptor sequence
>5i7mB (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
SLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLE
QALQFWKQSYNIRHSFYTPFSCLKIILSNPPSQGDYHGCPFRHSDPELLK
QKLQSYKISPGGISQILDLVKGTHYQVACQKYFEMIHNVDDCGFSLNHPN
QFFCESQRILNG
3D structure
PDB5i7m The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
ChainB
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 B P285 P286 C287 C367 C384 F386 C424 P444 P14 P15 C16 C72 C89 F91 C129 P149
Gene Ontology
Biological Process
GO:0006269 DNA replication, synthesis of primer

View graph for
Biological Process
External links
PDB RCSB:5i7m, PDBe:5i7m, PDBj:5i7m
PDBsum5i7m
PubMed28232525
UniProtP49643|PRI2_HUMAN DNA primase large subunit (Gene Name=PRIM2)

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