Structure of PDB 5i0h Chain B

Receptor sequence
>5i0hB (length=723) Species: 9606 (Homo sapiens) [Search protein sequence]
TEGTRVWLRENGQHFPSTVNVVFRTDYGQVFTYKQSTITHQKVTAMHPTN
EEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAG
LYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGA
GKTESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAK
TVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYH
IFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTISDQESFREVIT
AMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFKTALGRSAEL
LGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFE
WVIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEY
FNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKKLGLLALINEESH
FPQATDSTLLEKLHSQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGIL
EKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTRRPTVSSQFKDS
LHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRI
RKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQ
LGKTKVFLRESLEQKLEKRREEE
3D structure
PDB5i0h The myosin X motor is optimized for movement on actin bundles.
ChainB
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S159 G160 T164 N215 S218 S219 G437 E439
Catalytic site (residue number reindexed from 1) S148 G149 T153 N204 S207 S208 G426 E428
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B N104 P105 Y106 G160 G162 K163 T164 E165 N215 N93 P94 Y95 G149 G151 K152 T153 E154 N204
BS02 MG B T164 S219 T153 S208
BS03 BEF B S159 K163 N215 S218 S219 G437 S148 K152 N204 S207 S208 G426
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:5i0h, PDBe:5i0h, PDBj:5i0h
PDBsum5i0h
PubMed27580874
UniProtQ9HD67|MYO10_HUMAN Unconventional myosin-X (Gene Name=MYO10)

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