Structure of PDB 5hrw Chain B

Receptor sequence
>5hrwB (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
MTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPM
DMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHK
VLLETRRD
3D structure
PDB5hrw Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 64E B I683 F684 L687 Y696 M704 A735 I745 I29 F30 L33 Y42 M50 A81 I91
Gene Ontology
Biological Process
GO:0006338 chromatin remodeling
Cellular Component
GO:0016586 RSC-type complex

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Biological Process

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Cellular Component
External links
PDB RCSB:5hrw, PDBe:5hrw, PDBj:5hrw
PDBsum5hrw
PubMed27617704
UniProtQ86U86|PB1_HUMAN Protein polybromo-1 (Gene Name=PBRM1)

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