Structure of PDB 5hrq Chain B
Receptor sequence
>5hrqB (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB
5hrq
4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation.
Chain
B
Resolution
1.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
B
Q4 C7 L11 L15 C19 R22 G23 F24 F25 T30
Q4 C7 L11 L15 C19 R22 G23 F24 F25 T30
BS02
peptide
B
V2 H5
V2 H5
BS03
peptide
B
L6 S9 H10
L6 S9 H10
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:5hrq
,
PDBe:5hrq
,
PDBj:5hrq
PDBsum
5hrq
PubMed
28598606
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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