Structure of PDB 5hrq Chain B

Receptor sequence
>5hrqB (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB5hrq 4S-Hydroxylation of Insulin at ProB28 Accelerates Hexamer Dissociation and Delays Fibrillation.
ChainB
Resolution1.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B Q4 C7 L11 L15 C19 R22 G23 F24 F25 T30 Q4 C7 L11 L15 C19 R22 G23 F24 F25 T30
BS02 peptide B V2 H5 V2 H5
BS03 peptide B L6 S9 H10 L6 S9 H10
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:5hrq, PDBe:5hrq, PDBj:5hrq
PDBsum5hrq
PubMed28598606
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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