Structure of PDB 5hnk Chain B

Receptor sequence
>5hnkB (length=272) Species: 10726 (Tequintavirus T5) [Search protein sequence]
RNLMIVDGTNLGFRFKHNNSKKPFASSYVSTIQSLAKSYSARTTIVLGDK
GKSVFRLEHLPEYKGNRDEKYAQRTEEEKALDEQFFEYLKDAFELCKTTF
PTFTIRGVEADDMAAYIVKLIGHLYDHVWLISTKGDWDTLLTDKVSRFSF
TTRREYHLRDMYEHHNVDDVEQFISLKAIMGDLGDNIRGVEGIGAKRGYN
IIREFGNVLDIIDQLPLPGKQKYIQNLNASEELLFRNLILVDLPTYCVDA
IAAVGQDVLDKFTKDILEIAEQ
3D structure
PDB5hnk Direct observation of DNA threading in flap endonuclease complexes.
ChainB
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.11.-
3.1.11.3: exodeoxyribonuclease (lambda-induced).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B F32 K35 E210 G211 G213 K215 R216 F13 K16 E191 G192 G194 K196 R197
BS02 dna B F32 D68 K69 G70 K71 L76 R86 Y90 F105 T152 K153 G154 T171 F13 D49 K50 G51 K52 L57 R67 Y71 F86 T133 K134 G135 T152
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0017108 5'-flap endonuclease activity
GO:0035312 5'-3' DNA exonuclease activity
GO:0046872 metal ion binding
GO:0048256 flap endonuclease activity
GO:0051908 double-stranded DNA 5'-3' DNA exonuclease activity
GO:1990238 double-stranded DNA endonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0019086 late viral transcription
GO:0033567 DNA replication, Okazaki fragment processing
GO:0039693 viral DNA genome replication
Cellular Component
GO:0019034 viral replication complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5hnk, PDBe:5hnk, PDBj:5hnk
PDBsum5hnk
PubMed27273516
UniProtP06229|FEN_BPT5 Flap endonuclease (Gene Name=D15)

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