Structure of PDB 5hkp Chain B

Receptor sequence
>5hkpB (length=311) Species: 10090 (Mus musculus) [Search protein sequence]
TGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYN
RVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNA
MDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPEL
RERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAV
ASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKH
GAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTAAQM
GNEAVQQILSE
3D structure
PDB5hkp Crystal structure of a tankyrase 1-telomere repeat factor 1 complex.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R361 S363 L368 G371 Y372 L396 N401 Y405 H407 D425 W427 F429 E434 R440 R38 S40 L45 G48 Y49 L73 N78 Y82 H84 D102 W104 F106 E111 R117
External links
PDB RCSB:5hkp, PDBe:5hkp, PDBj:5hkp
PDBsum5hkp
PubMed27050267
UniProtQ6PFX9|TNKS1_MOUSE Poly [ADP-ribose] polymerase tankyrase-1 (Gene Name=Tnks)

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