Structure of PDB 5hc3 Chain B

Receptor sequence
>5hc3B (length=335) Species: 77133 (uncultured bacterium) [Search protein sequence]
KIAEDPRIDPRIKAIFSGGDVESREAMLEAASSEEATAVRDGLRVFLDAC
DNEEIAPSAGLKIEDYEFTSEPDGNIAKIQYIRPDSTDKLPCVYYIHGGG
MQSLSCYYGNYRAWGKIIASNGVAVAMVEFRNALVPSALPEVAPYPAGLN
DCVSGVKWVAAHADELGIDASRIIIAGESGGGNLTLAAGLRLKQEGSQDL
IQGLYALCPYIAGSWPSEDSPSSTENNGILLDLHNNQGAMGYGIEAYEMR
DPLAWPGFATEEDVSGLVPTFISVNECDPLRDEGINFYRLLLRAGVSAKC
RQVMGTIHGTEIFPIACPDVSRDTAASIANFCKGG
3D structure
PDB5hc3 Structural insights of a hormone sensitive lipase homologue Est22.
ChainB
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) G108 G109 S188 Y219 W224 D287 H317
Catalytic site (residue number reindexed from 1) G99 G100 S179 Y210 W215 D278 H308
Enzyme Commision number 3.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOL B G108 G109 S188 G99 G100 S179
BS02 GOL B D291 R298 D282 R289
BS03 GOL B Q211 F340 G343 G344 Q202 F331 G334 G335
Gene Ontology
Molecular Function
GO:0016298 lipase activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5hc3, PDBe:5hc3, PDBj:5hc3
PDBsum5hc3
PubMed27328716
UniProtH6BDX1

[Back to BioLiP]