Structure of PDB 5h9s Chain B

Receptor sequence
>5h9sB (length=133) Species: 9606 (Homo sapiens) [Search protein sequence]
VPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNP
RLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVG
DAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF
3D structure
PDB5h9s Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
ChainB
Resolution1.821 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TGZ B H49 R53 N62 W69 E72 R74 H47 R51 N60 W67 E70 R72 MOAD: Kd=87uM
PDBbind-CN: -logKd/Ki=4.06,Kd=87uM
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006915 apoptotic process
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular exosome

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Cellular Component
External links
PDB RCSB:5h9s, PDBe:5h9s, PDBj:5h9s
PDBsum5h9s
PubMed27416897
UniProtP47929|LEG7_HUMAN Galectin-7 (Gene Name=LGALS7)

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