Structure of PDB 5h9q Chain B

Receptor sequence
>5h9qB (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
PHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPR
LDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGD
AQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF
3D structure
PDB5h9q Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
ChainB
Resolution1.931 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TD2 B H33 H49 R53 N62 W69 E72 R74 H30 H46 R50 N59 W66 E69 R71 MOAD: Kd=38uM
PDBbind-CN: -logKd/Ki=4.42,Kd=38.0uM
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006915 apoptotic process
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular exosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5h9q, PDBe:5h9q, PDBj:5h9q
PDBsum5h9q
PubMed27416897
UniProtP47929|LEG7_HUMAN Galectin-7 (Gene Name=LGALS7)

[Back to BioLiP]