Structure of PDB 5h1k Chain B

Receptor sequence
>5h1kB (length=690) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMGIRNSMGQEPRTLPPSPNWYCARCSDAVPGGLFGFAARTSVFLVRVG
PGAGESPGTPPFRVIGELVGHTERVSGFTFSHHPGQYNLCATSSDDGTVK
IWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRN
DSQHLFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLR
GHDDEIHSIAWCPLPGEDCLSIGCYLATGSKDQTIRIWSCSRGRGVMILK
LPFLKERLWLTLHWPSNQPTQLVSSCFGGELLQWDLTQSWRRKYTLFSAS
SEGQNHSRIVFNLCPLQTEDDKQLLLSTSMDRDVKCWDIATLECSWTLPS
LGGFAYSLAFSSVDIGSLAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKS
KVTALCWHPTKEGCLAFGTDDGKVGLYDTYSNKPPQISSTYHKKTVYTLA
WGPPVPPMSLPSLALYSCGGEGIVLQHNPWKLSGEAFDINKLIRDTNSIK
YKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNT
ISWHHEHGSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPYR
TLSGHTAKITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRG
RLLCVAWSPLDPDCIYSGADDFCVHKWLTSMQDHSRPPQG
3D structure
PDB5h1k Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B N13 W14 Y15 R33 R66 R284 R335 R359 G380 F381 Y383 W422 K428 E556 K579 L580 N605 F705 N21 W22 Y23 R41 R74 R257 R308 R332 G353 F354 Y356 W395 K401 E523 K546 L547 N572 F672 PDBbind-CN: Kd=0.24uM
External links
PDB RCSB:5h1k, PDBe:5h1k, PDBj:5h1k
PDBsum5h1k
PubMed27881601
UniProtQ8TEQ6|GEMI5_HUMAN Gem-associated protein 5 (Gene Name=GEMIN5)

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