Structure of PDB 5gxu Chain B

Receptor sequence
>5gxuB (length=394) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
YTVFDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVG
VLCDNLSETVDEALRLLDMSPDTYFSLHPPFPPCNLRTALTRYACLLSSP
KKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAE
FPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPT
GRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIG
PGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRF
VESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDA
KGMARDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW
3D structure
PDB5gxu Structure of the Arabidopsis thaliana NADPH-cytochrome P450 reductase 2 (ATR2) provides insight into its function
ChainB
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y491 S492 C664 D709 W711
Catalytic site (residue number reindexed from 1) Y174 S175 C347 D392 W394
Enzyme Commision number 1.6.2.4: NADPH--hemoprotein reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B S416 Q458 R489 F490 Y491 S492 T507 C508 V511 M515 H521 G523 V524 C525 S526 T570 W711 S99 Q141 R172 F173 Y174 S175 T190 C191 V194 M198 H204 G206 V207 C208 S209 T253 W394
Gene Ontology
Molecular Function
GO:0003958 NADPH-hemoprotein reductase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0050660 flavin adenine dinucleotide binding
GO:0050661 NADP binding
Biological Process
GO:0009698 phenylpropanoid metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0009507 chloroplast
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5gxu, PDBe:5gxu, PDBj:5gxu
PDBsum5gxu
PubMed28103421
UniProtQ9SUM3|NCPR2_ARATH NADPH--cytochrome P450 reductase 2 (Gene Name=ATR2)

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