Structure of PDB 5gxo Chain B

Receptor sequence
>5gxoB (length=197) Species: 9606 (Homo sapiens) [Search protein sequence]
KHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALA
KGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRD
FGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTT
GLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACK
3D structure
PDB5gxo A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.15.1.1: superoxide dismutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B H50 H98 D183 H187 H26 H74 D159 H163
Gene Ontology
Molecular Function
GO:0004784 superoxide dismutase activity
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5gxo, PDBe:5gxo, PDBj:5gxo
PDBsum5gxo
PubMed28711502
UniProtP04179|SODM_HUMAN Superoxide dismutase [Mn], mitochondrial (Gene Name=SOD2)

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