Structure of PDB 5gu4 Chain B

Receptor sequence
>5gu4B (length=255) Species: 3988 (Ricinus communis) [Search protein sequence]
YPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQ
RFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAIT
HLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYS
TGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVI
TLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALM
VYRCA
3D structure
PDB5gu4 Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2
ChainB
Resolution1.55 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) T13 V81 E177 R180
Catalytic site (residue number reindexed from 1) T8 V76 E172 R175
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Q182 Y183 S203 R234 R235 F240 I247 P250 I251 Q177 Y178 S198 R229 R230 F235 I242 P245 I246
Gene Ontology
Molecular Function
GO:0030598 rRNA N-glycosylase activity
Biological Process
GO:0017148 negative regulation of translation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5gu4, PDBe:5gu4, PDBj:5gu4
PDBsum5gu4
PubMed27754366
UniProtP02879|RICI_RICCO Ricin

[Back to BioLiP]