Structure of PDB 5ggl Chain B

Receptor sequence
>5gglB (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]
VLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKR
VFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLG
SQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLS
3D structure
PDB5ggl Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of alpha-dystroglycan
ChainB
Resolution1.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 6ZC B R129 Y152 D179 E180 W206 R207 R32 Y55 D82 E83 W109 R110 MOAD: Kd=16.52mM
External links
PDB RCSB:5ggl, PDBe:5ggl, PDBj:5ggl
PDBsum5ggl
PubMed27493216
UniProtQ8WZA1|PMGT1_HUMAN Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (Gene Name=POMGNT1)

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