Structure of PDB 5fy7 Chain B

Receptor sequence
>5fy7B (length=446) Species: 9606 (Homo sapiens) [Search protein sequence]
DKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGL
FSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIA
KYAQYQASSFQESLREENEPFKTIKFGTNIDLSDNKKWKLQLHELTKLPA
FARVVSAGNLLTHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNIN
IGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVY
RFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEW
NKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLRE
ALVAAGKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHC
HDCARKTSKSLENFVVLEQYKMEDLIQVYDQFTLALSLSSSSAENL
3D structure
PDB5fy7 Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Succinate
ChainB
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.68: [histone H3]-trimethyl-L-lysine(27) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B H1014 E1016 H1094 H188 E190 H268
BS02 ZN B C1199 C1202 C1226 C1229 C373 C376 C400 C403
External links
PDB RCSB:5fy7, PDBe:5fy7, PDBj:5fy7
PDBsum5fy7
PubMed
UniProtO14607|UTY_HUMAN Histone demethylase UTY (Gene Name=UTY)

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