Structure of PDB 5fy1 Chain B

Receptor sequence
>5fy1B (length=446) Species: 9606 (Homo sapiens) [Search protein sequence]
DKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGL
FSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIA
KYAQYQASSFQESLREENEPFKTIKFGTNIDLSDNKKWKLQLHELTKLPA
FARVVSAGNLLTHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNIN
IGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVY
RFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEW
NKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLRE
ALVAAGKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHC
HDCARKTSKSLENFVVLEQYKMEDLIQVYDQFTLALSLSSSSAENL
3D structure
PDB5fy1 Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with N08619B
ChainB
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.68: [histone H3]-trimethyl-L-lysine(27) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C1278 C1281 C1308 C373 C376 C403
BS02 MN B H1093 E1095 H1173 H188 E190 H268
External links
PDB RCSB:5fy1, PDBe:5fy1, PDBj:5fy1
PDBsum5fy1
PubMed
UniProtO14607|UTY_HUMAN Histone demethylase UTY (Gene Name=UTY)

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