Structure of PDB 5fxz Chain B

Receptor sequence
>5fxzB (length=439) Species: 9606 (Homo sapiens) [Search protein sequence]
DKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGL
FSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIA
KYAQYQASSFQESLREENEPFKTIKFGTNIDLSDNKKWKLQLHELTKLPA
FARVVSAGNLLTHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNIN
IGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVY
RFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEW
NKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLRE
ALVAAGKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHC
HDCARKTSKSLENFVVLEQYKMEDLIQVYDQFTLALSLS
3D structure
PDB5fxz Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with Citrate
ChainB
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.68: [histone H3]-trimethyl-L-lysine(27) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B H1093 E1095 H1173 H188 E190 H268
BS02 ZN B C1278 C1281 C1305 C1308 C373 C376 C400 C403
External links
PDB RCSB:5fxz, PDBe:5fxz, PDBj:5fxz
PDBsum5fxz
PubMed
UniProtO14607|UTY_HUMAN Histone demethylase UTY (Gene Name=UTY)

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