Structure of PDB 5fxv Chain B

Receptor sequence
>5fxvB (length=439) Species: 9606 (Homo sapiens) [Search protein sequence]
DKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGL
FSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIA
KYAQYQASSFQESLREENEFKTIKFGTNIDLSDNKKWKLQLHELTKLPAF
ARVVSAGNLLTHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINI
GPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYR
FIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWN
KLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREA
LVAAGKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCH
DCARKTSKSLENFVVLEQYKMEDLIQVYDQFTLALSLSS
3D structure
PDB5fxv Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with N05859B
ChainB
Resolution1.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.68: [histone H3]-trimethyl-L-lysine(27) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C1278 C1281 C1305 C1308 C372 C375 C399 C402
BS02 MN B H1093 E1095 H1173 H187 E189 H267
BS03 MN1 B K1084 T1090 H1093 N1103 W1113 H1173 K178 T184 H187 N197 W207 H267
External links
PDB RCSB:5fxv, PDBe:5fxv, PDBj:5fxv
PDBsum5fxv
PubMed
UniProtO14607|UTY_HUMAN Histone demethylase UTY (Gene Name=UTY)

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