Structure of PDB 5fuy Chain B

Receptor sequence
>5fuyB (length=164) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
GRIELIIGPMFAGKTTELMRRVQRHKHAQRSCYIIKYTGDTTANVSVSNL
HDVGDEWRKYDVIAVDEGQFFPDVAAFCSKAADSGKVVIVSALDADYLQE
PFEEICLLVSRADSVVKLSAVCMECHNRKASFTYRTVKSDERKLVGGSDM
YMSVCRSCYETKRN
3D structure
PDB5fuy Cell Cycle Regulation and Novel Structural Features of Thymidine Kinase, an Essential Enzyme in Trypanosoma Brucei.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.21: thymidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QBT B M214 K218 E286 F289 L312 D315 Y316 T352 R361 K362 L363 V364 G365 Y370 M10 K14 E67 F70 L93 D96 Y97 T133 R142 K143 L144 V145 G146 Y151
BS02 ZN B C341 C344 C374 C377 C122 C125 C155 C158
Gene Ontology
Molecular Function
GO:0004797 thymidine kinase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:5fuy, PDBe:5fuy, PDBj:5fuy
PDBsum5fuy
PubMed27426054
UniProtQ38CF2

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