Structure of PDB 5ft6 Chain B

Receptor sequence
>5ft6B (length=399) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
NVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEATQQFYSLSAGNVH
RSQFAEAQRLTARYEAAREKVAQLLNAPDDKTIVWTRGTTESINMVAQCY
ARPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVD
LLPELITPRSRILALGQMSNVTGGCPDLARAITFAHSAGMVVMVDGAQGA
VHFPADVQQLDIDFYAFSGHKLYGPTGIGVLYGKSELLEAMSPWLGGGKM
VHEVSFDGFTTQSAPWKLEAGTPNVAGVIGLSAALEWLADYDINQAESWS
RSLATLAEDALAKRPGFRSFRCQDSSLLAFDFAGVHHSDMVTLLAEYGIA
LRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAVDRALELLV
3D structure
PDB5ft6 Mechanism of Sulfur Transfer Across Protein-Protein Interfaces: The Cysteine Desulfurase Model System
ChainB
Resolution2.049 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H119 D196 A198 Q199 K222 R353 C358
Catalytic site (residue number reindexed from 1) H118 D195 A197 Q198 K221 R352 C357
Enzyme Commision number 2.8.1.7: cysteine desulfurase.
3.13.1.-
4.4.1.16: selenocysteine lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B T90 T91 H119 D196 A198 Q199 S219 K222 T89 T90 H118 D195 A197 Q198 S218 K221
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008826 cysteine sulfinate desulfinase activity
GO:0009000 selenocysteine lyase activity
GO:0016740 transferase activity
GO:0016783 sulfurtransferase activity
GO:0016787 hydrolase activity
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0031071 cysteine desulfurase activity
Biological Process
GO:0000096 sulfur amino acid metabolic process
GO:0006534 cysteine metabolic process
GO:0016226 iron-sulfur cluster assembly
GO:0016261 selenocysteine catabolic process
GO:0019448 L-cysteine catabolic process
GO:0072348 sulfur compound transport
Cellular Component
GO:1990221 L-cysteine desulfurase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ft6, PDBe:5ft6, PDBj:5ft6
PDBsum5ft6
PubMed
UniProtQ46925|CSDA_ECOLI Cysteine desulfurase CsdA (Gene Name=csdA)

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