Structure of PDB 5fsx Chain B

Receptor sequence
>5fsxB (length=232) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
EFVTYSGESSPTRTRILSAALSPAERAIFDVPIEKWLSIDRSSLSGWKCA
VPRPVTIEQLRPVDPSDAILRHIALYRGPVTDLQLDAIVNAANTRCLGGG
GVDGAIHRVAGPLLLRECATFNGCQTGECRLTKGYQLPARYVLHTVGPVG
ERPDMLRKCYRSILSLALKNGLRSIGFCCVSTGVYGYPLLPATRIALGET
RKFLEEHGGALDMCCFACFQEDEYKTYEKCVG
3D structure
PDB5fsx Proximal Adp-Ribose Hydrolysis in Trypanosomatids is Catalyzed by a Macrodomain.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B G130 V131 A134 C208 S210 G212 V213 Y214 F248 E252 G101 V102 A105 C179 S181 G183 V184 Y185 F219 E223 MOAD: Ka=540M^-1
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:5fsx, PDBe:5fsx, PDBj:5fsx
PDBsum5fsx
PubMed27064071
UniProtC9ZP98

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