Structure of PDB 5fro Chain B

Receptor sequence
>5froB (length=182) Species: 11963 (Human spumaretrovirus) [Search protein sequence]
DRPQKPFDKFFIDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPTKAPSTSA
TVKSLNVLTSIAIPKVIHSDQGAAFTSSTFAEWAKERGIHLEFSTPYHPQ
SSGKVERKNSDIKRLLTKLLVGRPTKWYDLLPVVQLALNNTYSPVLKYTP
HQLLFGIDSNTPFANQDTLDLTREEELSLLQE
3D structure
PDB5fro HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant Mutant Integrases.
ChainB
Resolution2.67 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D128 D185 D13 D70
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:5fro, PDBe:5fro, PDBj:5fro
PDBsum5fro
PubMed26808478
UniProtP14350|POL_FOAMV Pro-Pol polyprotein (Gene Name=pol)

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