Structure of PDB 5fr2 Chain B

Receptor sequence
>5fr2B (length=178) Species: 9913 (Bos taurus) [Search protein sequence]
VNYKPPAQKSIQEIQELDKDDESLRKYKEALLGRVSADPNVPNVVVTRLT
LVCSTAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRVNREIVSGM
KYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPMEEAPKGMLARGSYN
IKSRFTDDDRTDHLSWEWNLTIKKEWKD
3D structure
PDB5fr2 Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation.
ChainB
Resolution3.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAR B L77 L86 E87 F102 Y110 I112 Q130 L51 L60 E61 F76 Y84 I86 Q104
BS02 BGC B P68 N69 V70 R120 T187 P42 N43 V44 R94 T161
Gene Ontology
Molecular Function
GO:0005094 Rho GDP-dissociation inhibitor activity
GO:0005096 GTPase activator activity
Biological Process
GO:0007266 Rho protein signal transduction
GO:0071526 semaphorin-plexin signaling pathway
Cellular Component
GO:0001772 immunological synapse
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:5fr2, PDBe:5fr2, PDBj:5fr2
PDBsum5fr2
PubMed26719334
UniProtP19803|GDIR1_BOVIN Rho GDP-dissociation inhibitor 1 (Gene Name=ARHGDIA)

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