Structure of PDB 5fm0 Chain B

Receptor sequence
>5fm0B (length=247) Species: 1423 (Bacillus subtilis) [Search protein sequence]
ETFYSVRMRASMNGGKHISGGERLIPFHEMKHTVNALLEKGLSHSRGKPD
FMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVSRDVI
EKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDANFEKW
ALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVAGKKM
GYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEED
3D structure
PDB5fm0 Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.
ChainB
Resolution2.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.2.1.14: 6-carboxyhexanoate--CoA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WAQ B E31 G124 A125 R145 V146 R170 I171 L177 S194 D195 Y199 T201 Y203 Y211 R213 R227 E22 G115 A116 R136 V137 R161 I162 L168 S185 D186 Y190 T192 Y194 Y202 R204 R218
BS02 PPV B S28 G29 K49 H53 R145 S19 G20 K40 H44 R136
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0042410 6-carboxyhexanoate-CoA ligase activity
Biological Process
GO:0009102 biotin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5fm0, PDBe:5fm0, PDBj:5fm0
PDBsum5fm0
PubMed28414710
UniProtP53559|BIOW_BACSU 6-carboxyhexanoate--CoA ligase (Gene Name=bioW)

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