Structure of PDB 5flg Chain B

Receptor sequence
>5flgB (length=252) Species: 1423 (Bacillus subtilis) [Search protein sequence]
ETFYSVRMRASMNGSHEDGGKHISGGERLIPFHEMKHTVNALLEKGLSHS
RGKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGV
SRDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDA
NFEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYV
AGKKMGYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWE
ED
3D structure
PDB5flg Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.
ChainB
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.2.1.14: 6-carboxyhexanoate--CoA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PML B R170 I171 S194 Y199 Y211 R213 R166 I167 S190 Y195 Y207 R209
BS02 ANP B H26 S28 G29 E31 K49 H53 R123 G124 A125 R145 V146 L177 D195 R227 H22 S24 G25 E27 K45 H49 R119 G120 A121 R141 V142 L173 D191 R223
BS03 MG B D195 D196 D191 D192
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0042410 6-carboxyhexanoate-CoA ligase activity
Biological Process
GO:0009102 biotin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5flg, PDBe:5flg, PDBj:5flg
PDBsum5flg
PubMed28414710
UniProtP53559|BIOW_BACSU 6-carboxyhexanoate--CoA ligase (Gene Name=bioW)

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