Structure of PDB 5fg5 Chain B

Receptor sequence
>5fg5B (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
QLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFTM
KQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGAV
LRQARRQA
3D structure
PDB5fg5 Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe
ChainB
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5XF B I652 F653 E655 V657 P658 E661 N708 F714 I24 F25 E27 V29 P30 E33 N80 F86 BindingDB: IC50=50nM,Kd=13nM
External links
PDB RCSB:5fg5, PDBe:5fg5, PDBj:5fg5
PDBsum5fg5
PubMed
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

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