Structure of PDB 5fau Chain B

Receptor sequence
>5fauB (length=795) Species: 207559 (Oleidesulfovibrio alaskensis G20) [Search protein sequence]
SGIPDGPTPRHVKLKENFLKQVPSITVQRAVAITKIAKENPGLPKPLLRA
KTFRYCCETAPLVIQDHELIVGSPNGAPRAGAFSPEVAWRWLQDELDTIG
SRPQDPFYISEEDKKVLREEVFPFWQNKSVDEFCEGQYREADLWEMSGES
FVSDCSYHAVNGGGDSNPGYDVILMKKGMLDIQREAREKLEQLDYANPED
IDKIYFYKSVIETAEGVMIYARRLSAYAAELAARETDPRRKAELQKISEV
NARVPAHAPSNFWEAIQAVWTVESLLVVEENQTGMSIGRVDQYMYPFYRA
DIDSGRLTEYEAFDLAGCMLVKMSEMMWITSEGASKFFAGYQPFVNMCVG
GVTREGHDATNDLTYMLMDAVRHVRIYQPTLATRVHNKSPQKYLKKIVDV
IRSGMGFPAVHFDDAHIKMMLAKGVSIEDARDYCLMGCVEPQKSGRLYQW
TSTGYTQWPICIELVLNHGVPLWYGKKVTPDMGDLSQYDTYEKFEAAVKE
QIRWITKNTSVATVISQRAHRELAPKPLMSLMYEGCMESGRDVSAGGAMY
NFGPGVVWSGLATYVDSMAAIKKLVYDDRKYTLAQLNEALKADFAGYDQI
LADCLAAPKYGNDDDYADMIAADLVHFTETEHRKYKTLYSVLSHGTLSIS
NNTPFGQLLGASANGRRAWMPLSDGISPTQGADYKGPTAIIKSVSKMAND
NMNIGMVHNFKLMSGLLDTPEGENGLITLIRTACMLGNGEMQFNYLDNEL
LLDAQKHPEKYRDLVVRVAGYSAFFVELCKDVQDEIISRTMLHGF
3D structure
PDB5fau Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
ChainB
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F395 G488 C489 G821
Catalytic site (residue number reindexed from 1) F344 G437 C438 G770
Enzyme Commision number 4.3.99.4: choline trimethylamine-lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CHT B Y208 D216 G488 C489 E491 Y157 D165 G437 C438 E440
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016840 carbon-nitrogen lyase activity
GO:0033265 choline binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0042426 choline catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5fau, PDBe:5fau, PDBj:5fau
PDBsum5fau
PubMed27642068
UniProtQ30W70|CUTC_OLEA2 Choline trimethylamine-lyase (Gene Name=cutC)

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