Structure of PDB 5f8f Chain B

Receptor sequence
>5f8fB (length=361) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
SSGLVPRGSHMETTEEFGNRFVAAIDSAGLAILVSVGHQTGLLDTMAGLP
PATSMEIAEAAGLEERYVREWLGGMTTGQIVEYDAGSSTYSLPAHRAGML
TRAAGPDNLAVIAQFVSLLGEVEQKVIRCFREGGGVPYSEYPRFHKLMAE
MSGMVFDAALIDVVLPLVDGLPDRLRSGADVADFGCGSGRAVKLMAQAFG
ASRFTGIDFSDEAVAAGTEEAARLGLANATFERHDLAELDKVGAYDVITV
FDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASSQLEDNVGVPLSTYL
YTTSLMHCMTVSLALDGAGLGTVWGRQLATSMLADAGFTDVTVAEIESDV
LNNYYIARKLE
3D structure
PDB5f8f Crystal structure of Rv2258c from Mycobacterium tuberculosis H37Rv, an S-adenosyl-l-methionine-dependent methyltransferase
ChainB
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SFG B Y132 M142 S146 G179 D202 F203 D229 L230 F245 D246 Q251 Y138 M148 S152 G185 D208 F209 D235 L236 F251 D252 Q257
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5f8f, PDBe:5f8f, PDBj:5f8f
PDBsum5f8f
PubMed26772148
UniProtO53532|Y2258_MYCTU S-adenosylmethionine-dependent methyltransferase Rv2258c (Gene Name=Rv2258c)

[Back to BioLiP]