Structure of PDB 5f1h Chain B

Receptor sequence
>5f1hB (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
ESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTM
KDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKM
MSKERLLALKRSM
3D structure
PDB5f1h Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor.
ChainB
Resolution1.82 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5U6 B F44 F45 P48 V49 I53 N100 Y106 F24 F25 P28 V29 I33 N80 Y86 MOAD: Kd=14.1nM
BindingDB: Kd=47nM,IC50=75nM
External links
PDB RCSB:5f1h, PDBe:5f1h, PDBj:5f1h
PDBsum5f1h
PubMed26914985
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

[Back to BioLiP]