Structure of PDB 5ey0 Chain B

Receptor sequence
>5ey0B (length=253) Species: 418127 (Staphylococcus aureus subsp. aureus Mu3) [Search protein sequence]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILG
SSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPP
ENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVI
GMEILREKHSEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGL
LIASKVADRVGITRSVIVNALRKLESAGVIESRSLKGTFIKVKKEKFLDE
LEK
3D structure
PDB5ey0 The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ILE B R61 M65 Y75 V97 F98 R61 M65 Y75 V97 F98
BS02 GTP B V22 F24 S43 R44 R45 K47 L49 E157 K158 V22 F24 S43 R44 R45 K47 L49 E157 K158 MOAD: Kd=2.26mM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005525 GTP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5ey0, PDBe:5ey0, PDBj:5ey0
PDBsum5ey0
PubMed27596595
UniProtA7X1N2|CODY_STAA1 Global transcriptional regulator CodY (Gene Name=codY)

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