Structure of PDB 5eua Chain B

Receptor sequence
>5euaB (length=250) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
DFEHAISDLEAHNQAKIGVALVSENGNLIQGYRANERFAMCSTFKLPLAA
LVLSRIDAGEENPERKLHYDSAFLEEYAPAAKRYVATGYMTVTEAIQSAL
QLSDNAAANLLLKEVGGPPLLTKYFRSLGDKVSRLDRIERDTTTPMSMAQ
TVSKLIFGDTLTYKSKGQLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSC
ANGGRNDVAFFITTAGKKYVLSVYTNAPELQGEERALLIASVAKLARQYV
3D structure
PDB5eua Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and Its Complexes with Moxalactam and Imipenem.
ChainB
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S62 K65 S123 K227 S230
Catalytic site (residue number reindexed from 1) S42 K45 S103 K196 S199
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3P7 B S62 K65 S123 N125 T228 G229 S230 S42 K45 S103 N105 T197 G198 S199
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
Biological Process
GO:0017001 antibiotic catabolic process
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:5eua, PDBe:5eua, PDBj:5eua
PDBsum5eua
PubMed27671060
UniProtQ3SAW3

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