Structure of PDB 5er8 Chain B

Receptor sequence
>5er8B (length=304) Species: 1214568 (Diaporthe amygdali) [Search protein sequence]
EFKYSEVVEPSTYYTEGLCEGIDVRKSKFTTLEDRGAIRAHEDWNKHIGP
CREYRGTLGPRFSFISVAVPECIPERLEVISYANEFAFLHDDVTDAGKKR
IQSQLFLEMLAIDPECAKTTMKSWARFVEVGSSRETRFVELAKYIPYRIM
DVGEMFWFGLVTFGLGLHIPDHELELCRELMANAWIAVGLQNDIWSWPKE
RDAATLHGKDHVVNAIWVLMQEHQTDVDGAMQICRKLIVEYVAKYLEVIE
ATKNDESISLDLRKYLDAMLYSISGNVVWSLECPRYNPDVSFNKTQLEWM
RQGL
3D structure
PDB5er8 Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase.
ChainB
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A69 F89 F165 E194 W319
Catalytic site (residue number reindexed from 1) A68 F88 F127 E154 W279
Enzyme Commision number 2.5.1.29: geranylgeranyl diphosphate synthase.
4.2.3.43: fusicocca-2,10(14)-diene synthase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN B D92 D96 D91 D95
BS02 MN B D92 D96 D91 D95
BS03 MN B R188 N232 S236 E240 R148 N192 S196 E200
BS04 NRD B D92 R188 V192 W225 N232 S236 K239 E240 R325 Y326 D91 R148 V152 W185 N192 S196 K199 E200 R285 Y286
BS05 MN B H212 S297 H172 S257
External links
PDB RCSB:5er8, PDBe:5er8, PDBj:5er8
PDBsum5er8
PubMed26734760
UniProtA2PZA5|FC1_PHOAM Fusicoccadiene synthase (Gene Name=PaFS)

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