Structure of PDB 5egv Chain B

Receptor sequence
>5egvB (length=232) Species: 9606 (Homo sapiens) [Search protein sequence]
LSLTADQMVSALLDAEPPILYSEYDPTFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHM
SNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB5egv Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.863 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 Q375 V376 L379 D538 L539 E542 M543 I49 K53 L63 Q66 V67 L70 D221 L222 E225 M226
BS02 5OS B L346 T347 E353 L387 M388 F404 L37 T38 E44 L78 M79 F95 BindingDB: EC50=266nM
External links
PDB RCSB:5egv, PDBe:5egv, PDBj:5egv
PDBsum5egv
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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