Structure of PDB 5egp Chain B

Receptor sequence
>5egpB (length=281) Species: 1437362 (Aspergillus fumigatus Z5) [Search protein sequence]
IQNMFQTKSFVDRYKYTEKLTGLYAQTLVDYSGVANTSQKPLVVLDNACG
IGAVSSVLNHTLQDEAKKTWKLTCGDLSEGMLETTKRRLQDEGWVNAETK
IVNALDTGLPDGHYTHVFVAFGFQSFPDANAALKECFRILASGGILASST
WQNFNWIPIMKAAIETIPGNLPFPTQKEFITLHNAGWDSESYIQSELEKL
GFRDVKVIPVPKETSIPIDEFFEVCMMIIPYLLPKFWTEEQRESHEKDVP
MVLRQYLQDTYGANGQVPLEAVALITTGLKP
3D structure
PDB5egp Sequential Inactivation of Gliotoxin by the S-Methyltransferase TmtA.
ChainB
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.9: thiol S-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH B F11 Y20 T27 A54 C55 G56 D82 L83 M87 N109 A110 A126 F127 F132 F5 Y14 T21 A48 C49 G50 D76 L77 M81 N103 A104 A120 F121 F126
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5egp, PDBe:5egp, PDBj:5egp
PDBsum5egp
PubMed26808594
UniProtQ4X158|TMTA_ASPFU Gliotoxin thiomethyltransferase GtmA (Gene Name=tmtA)

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