Structure of PDB 5ego Chain B

Receptor sequence
>5egoB (length=63) Species: 9606 (Homo sapiens) [Search protein sequence]
RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQN
RRVKEKKVLAKVK
3D structure
PDB5ego Impact of cytosine methylation on DNA binding specificities of human transcription factors.
ChainB
Resolution2.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B R217 R220 I221 Y223 Q259 I262 N266 K270 R1 R4 I5 Y7 Q43 I46 N50 K54
BS02 dna B K219 R220 Q265 R268 K272 K3 R4 Q49 R52 K56
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:5ego, PDBe:5ego, PDBj:5ego
PDBsum5ego
PubMed28473536
UniProtQ92826|HXB13_HUMAN Homeobox protein Hox-B13 (Gene Name=HOXB13)

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