Structure of PDB 5efk Chain B

Receptor sequence
>5efkB (length=355) Species: 7955 (Danio rerio) [Search protein sequence]
ITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSRCHRIPAR
LATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFISNESYTCA
LLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCFFNTAALT
ARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLHRYEDGAF
FPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHLVMPIARE
FAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAGRVLIILE
GGFNLTSISESMSMCTSMLLGDSPPSLHLTPLKTSATVSINNVLRAHAPF
WSSLR
3D structure
PDB5efk Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.
ChainB
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.98: histone deacetylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B N530 S531 P571 G582 F583 H614 F643 G743 F745 N88 S89 P129 G140 F141 H172 F201 G301 F303
BS02 ZN B D612 H614 D705 D170 H172 D263
BS03 MCM B P464 L712 P22 L270
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