Structure of PDB 5e9e Chain B

Receptor sequence
>5e9eB (length=261) Species: 44689 (Dictyostelium discoideum) [Search protein sequence]
ISSETGEMGILWEFDPIINKWIRLSMKLKVERKPFAEGALREAYHTVSLG
VGTDENYPLGTTKLFPPIEMISPISKNNEAMTQLKNGTKFVLKLYKKEAE
QQASRELYFEDVKMQMVCRDWGNKFNQKKPPKKIEFLMSWVVELIDRSPS
SNGQPILCSIEPLLVGEFKKNNSNYGAVLTNRSTPQAFSHFTYELSNKQM
IVVDIQGVDDLYTDPQIHTPDGKGFGLGNLGKAGINKFITTHKCNAVCAL
LDLDVKLGGVL
3D structure
PDB5e9e Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) alpha-kinase domain apoenzyme reveals a novel autoinhibited conformation.
ChainB
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.7: [myosin heavy-chain] kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP B F586 A587 E588 G589 A590 L591 R592 V643 K645 E713 L716 F720 K722 D766 F35 A36 E37 G38 A39 L40 R41 V91 K93 E161 L164 F168 K170 D214
BS02 ZN B H742 H794 C796 C800 H190 H242 C244 C248
Gene Ontology
Molecular Function
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5e9e, PDBe:5e9e, PDBj:5e9e
PDBsum5e9e
PubMed27211275
UniProtP42527|MHCKA_DICDI Myosin heavy chain kinase A (Gene Name=mhkA)

[Back to BioLiP]